^Ruffle JK. Molecular neurobiology of addiction: what's all the (Δ)FosB about?. Am J Drug Alcohol Abuse. November 2014, 40 (6): 428–437. PMID 25083822. doi:10.3109/00952990.2014.933840. Propofol is a general anaesthetic, however its abuse for recreational purpose has been documented (120). Using control drugs implicated in both ΔFosB induction and addiction (ethanol and nicotine), similar ΔFosB expression was apparent when propofol was given to rats. Moreover, this cascade was shown to act via the dopamine D1 receptor in the NAc, suggesting that propofol has abuse potential (119)
^Miner, JR; Burton, JH. Clinical practice advisory: Emergency department procedural sedation with propofol. Annals of Emergency Medicine. August 2007, 50 (2): 182–7. PMID 17321006. doi:10.1016/j.annemergmed.2006.12.017.
^Wakai, A; Blackburn, C; McCabe, A; Reece, E; O'Connor, G; Glasheen, J; Staunton, P; Cronin, J; Sampson, C; McCoy, SC; O'Sullivan, R; Cummins, F. The use of propofol for procedural sedation in emergency departments.. The Cochrane Database of Systematic Reviews. 2015-07-29, 7: CD007399. PMID 26222247. doi:10.1002/14651858.CD007399.pub2.